25 years ago today, R.E.M. released Losing My Religion, which signaled the exact midpoint between early R.E.M. and later R.E.M. After this megahit, things would never be the same for them, or for music in general. A #1 worldwide hit with mandolin? Really? No one could call it calculated. If anything, this track was a bit of a throwback to Fables-era R.E.M. and a far cry from the brash rock of the preceding three albums. The decade-long run of college rock (aka alternative, or indie) had now well and truly bubbled up to the mainstream surface. It’s no mistake that mere months later, Nevermind would top the charts as well, heralding a sea change in what kinds of music were popular. Here’s the very first live performance of the song.